We seek highly motivated postdoctoral scientists (experimental and computational) to investigate the genome regulatory events that drive developmental decisions and their expression. The project is a collaboration between the laboratories of Julie Ahringer (Gurdon Institute) and John Marioni (Cambridge CRUK Institute).
Postdoctoral positions are available in the lab of Professor Ya-Ming Hou at Thomas Jefferson University, Sidney Kimmel Medical College. We focus on tRNA epigenetic modifications and explore their roles in gene expression at the codon level and in response to cellular stress, which are new concepts at the cutting edge of molecular biology. We use a synthetic biology approach to determine how modifications impact cell fitness in engineered genomes with synonymous replacement of codons.